Type of I.P :
Patent A government authority or licence conferring a right or title for a set period, especially the sole right to exclude others from making, using, or selling an invention.
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Patent Title : A Method for Recovering an Intracellular Polyhydroxyalkanoates (PHA)
Patent Registration No : PI2010000891
R & D
R&D The invention is at the lab stage or proof concept stage
Pre-Commercial The invention is currently in the process of field testing
Ready For Market Invention is ready to be licensed out or sold
Selling Method :
Exclusive Licensing No person or company other than the named licensee can exploit the relevant intellectual property rights. Importantly, the licensor is also excluded from exploiting the intellectual property rights.
Licensing Authorization to use a particular patent. Licensee may not be the only one licensed to exploit the intellectual property.
Assignment The sale of ownership to the individual assigning the intellectual property.
Product Year :
The present invention relates to a method to recover an intracellular polyhydroxyalkanoates (PHA). The method includes the steps of (a) separating culture medium containing PHA-rich cells using centrifugation, (b) rinsing pellet obtained from setp (a) with distilled water, (c) freeze-drying pellet obtained in step (b), (d) adding distilled water to the freeze-dried sample, (e) separating non-PHA cellular material (NPCM) from PHA granules, (f) washing the pallet containing PHA from step (e) by distilled water and centrifuging for producing final pellet, and (g) freeze-drying the pellet produced from step (f).
Due to the similar mechanical properties to synthetic plastics, complete biodegradability and potential chemical pools for useful chiral compounds, PHAs have been drawn much attention for commercial application. But large scale industrialized production of PHAs has not been realized internationally. Actually, important contributors to cost of production are the fermentation substrate and downstream processing. Therefore, upstream to downstream strategies including development of better bacterial strains, efficient fermentation and recovery processes have been devoted to lower the production cost of PHAs.
PHA is an energy and/or carbon storage material synthesized and accumulated intracellular^ by numerous microorganisms, usually when essential nutritional elements such as nitrogen, phosphorous, oxygen, sulphur, or potassium is limited in the presence of excess carbon source. PHA provides the only renewable source of truly biodegradable plastic and the component elements are readily liberated as C02 and water, by degradation of microorganisms.