Type of I.P :
Patent A government authority or licence conferring a right or title for a set period, especially the sole right to exclude others from making, using, or selling an invention.
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Others Trade Secerts, Innovative Step, Creative etc
Patent Title : Antifreeze Peptides Derived from Fungal Protein
Patent Registration No : PI20095541
R & D
R&D The invention is at the lab stage or proof concept stage
Pre-Commercial The invention is currently in the process of field testing
Ready For Market Invention is ready to be licensed out or sold
Selling Method :
Exclusive Licensing No person or company other than the named licensee can exploit the relevant intellectual property rights. Importantly, the licensor is also excluded from exploiting the intellectual property rights.
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Assignment The sale of ownership to the individual assigning the intellectual property.
Product Year :
The present invention discloses antifreeze peptides derived from the fungal protein of leucosporidium antarcticum that have high antifreeze activity and the antifreeze peptides of the present invention decrease the freezing point of an aqueous solution and record a molecular weight of between 2,482 and 3,68 kDa.
In order to reach increased expression levels, tandem repeats of the AFP gene (up to eight copies) have been cloned. In most cases the genes are efficiently expressed and the products secreted.
The expression level amounts to approximately 100 mg/l in the culture medium. In a number of genetic constructs the genes are directly linked and expressed as AFP multimers. In other constructs linker regions have been inserted between the AFP gene copies, that allow the peptide to be processed by specific proteinases, either from the endogenous yeast proteolytic system or from a non-yeast source.
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